Advise feminine patients of reproductive probable that utilization of OXYCONTIN for an prolonged timeframe in the course of pregnancy can lead to neonatal opioid withdrawal syndrome, which can be existence-threatening Otherwise acknowledged and addressed [see WARNINGS AND Safeguards and Use In Precise Populations].
Request your doctor or pharmacist if you should have naloxone available to treat opioid overdose. Educate your family or home customers concerning the indications of an opioid overdose and how to take care of it.
Usage of oxycodone hydrochloride tablets is associated with improved opportunity threats and may be utilised only with warning in the following circumstances: acute alcoholism; adrenocortical insufficiency (e.g., Addison's illness); convulsive Diseases; CNS depression or coma; delirium tremens; debilitated clients; kyphoscoliosis involved with respiratory depression; myxedema or hypothyroidism; prostatic hypertrophy or urethral stricture; intense impairment of hepatic, pulmonary or renal function; and poisonous psychosis.
six relative to that of oxycodone. Oxymorphone is present inside the plasma only in lower concentrations. The analgesic action profile of other metabolites is not really recognized at present.
If another person has overdosed and it has serious signs which include passing out or hassle respiration, provide them with naloxone if offered, then phone 911. If the individual is awake and it has no signs, phone a poison Management Heart instantly.
Step #3: Shut observation and titration are warranted right up until discomfort management is secure on the new opioid. Watch patients for symptoms and signs and symptoms of opioid withdrawal or for indications of over-sedation/toxicity soon after changing sufferers to OXYCONTIN.
Don't abruptly discontinue OXYCONTIN in individuals who might be more info bodily depending on opioids. Immediate discontinuation of opioid analgesics in people who are bodily depending on opioids has resulted in really serious withdrawal indicators, uncontrolled discomfort, and suicide.
Moreover, abuse of opioids can arise while in the absence of correct dependancy which is characterized by misuse for nonmedical applications, generally in combination with other more info psychoactive substances. Careful report-retaining of prescribing info, together with quantity, frequency, and renewal requests is strongly recommended.
The above information is meant to complement, not substitute for, the skills and judgment of one's health and fitness care Skilled. You need to talk to your well being care Qualified just before getting any drug, changing website your diet, or commencing or discontinuing any system of treatment.
Be certain you understand how to acquire oxycodone and what other drugs it is best to avoid getting with it. See also Drug Interactions area. Get professional medical help without delay if any click here of such very significant Unwanted effects come about: sluggish/shallow breathing, strange lightheadedness, intense drowsiness/dizziness, issue waking up.
Keep away from taking in grapefruit or consuming grapefruit juice when employing this medication unless your medical doctor or pharmacist says chances are you'll achieve this safely. Grapefruit can increase the potential for Unwanted effects get more info with this medicine. Talk to your physician or pharmacist For additional facts.
OXYCONTIN® exposes sufferers and other people to your pitfalls of opioid addiction, abuse, and misuse, which can cause overdose and Dying.
Oxycodone hydrochloride tablets, like all opioid analgesics, might result in critical hypotension in a person whose potential to maintain blood pressure is compromised by a depleted blood volume, or following concurrent administration with drugs including phenothiazines or other agents which compromise vasomotor tone.
Although it helps Lots of individuals, this medication may occasionally result in addiction. This danger could be larger In case you have a substance use disorder (such as overuse of or habit to drugs/alcohol).